The study aimed to ascertain the profile and extent of use of the CPU Henry Luce III Library and its role in the individual and professional development as assessed by the users. Furthermore, this study assessed the profile of the library in terms of its human resources, collections, physical resources, and financial resources. conducted in June 2008 at the Central Philippine University, the study utilized 382 randomly selected library users from the different colleges. The stratified proportional random sampling was used to select participants of the study. The variables included the profile, extent of use, user's representation by college and the role of the CPU Henry Luce III Library in their individual and professional development. To generate the quantitative data, this survey research used the researcher-made questionnaire. Part I of which surveyed the profile of the CPU Henry Luce III Library in terms of human resources, collections, physical resources using the library data base. Part II was used to assess the role of the CPU Henry Luce III Library in the individual and professional development. Both the descriptive and inferential statistical tools were employed in the treatment of data which included counts, percentage analysis, means, and standard deviations for the descriptive data analysis; and One-way Analysis of Variance Set at .05 alpha for the inferential data analysis. The study found out that the CPU Henry Luce III Library had a total of 163 human resources; 304,756 collections; the circulation and reserve section occupied the widest area while the Centraliana section and the staff lounge, covered the smallest spaces. The total financial resources was Php17,405,000.00. Priorities were allocated for books, supplies and materials and salaries of professional staff. All the 163 human resources were readily available to serve the users and the 892,256 collections of books were utilized by the users. Another bigger number of collections utilized was the Meyer-Asian collections. Upon further analysis of the results the on-line databases, dissertation abstracts international updated, general references and books were highly used. Moderately used were periodicals, newspapers, magazines, and CD-ROM's while the remaining collections were used to a low extent. The spaces occupied by the different sections of the library were fully utilized; the physical resources mostly visited/availed were the Reference and Bibliography Section. The users differed significantly in their assessment of the role of the CPU Henry Luce III Library in individual and professional development.