This research ascertained the knowledge and attitude towards human sexuality: bases for the development of a guidance program in sex education. Conducted November 2005 to January 2006, this study utilized a questionnaire and a research-made attitudinal inventory for data-gathering. The statistical tools used were ranks, frequency counts, percentages, ANOVA, and Pearson's r. Alpha lvele was set at .05. Majority of the respondents were older, enrolled in BS Industrial Technology , and with high school educated parents. Respondents had intact family structure, more than a half reside in rural areas, and a large minority had priests/ministers as sources of knowledge and information regarding human sexuality. Respondents had "very adequate" knowledge about human sexuality. Respondents differed significantly in their knowledge about human sexuality whereas there was no significant difference noted in the attitude toward human sexuality among the students. The personal factors as (a) sex, (b) age, (c) degree pursued, and (d) parents' educational attainment, and environmental variables as (a) family situation, (b) residence, and (c) source of knowledge and information about human sexuality were used. The relationship between the knowledge about human sexuality and attitude towards it were the dependent factors. The results had very high correlation. A very high correlation existed between the students' knowledge about their attitude towards human sexuality.