This experimental study was conducted o determine the mutagenic effect of electromganetic cellular phone emissions on staphyloccocus aureus. The experiments have four treatments based on the duration of exposure, specifically, 30, 60, 90 and 120 minutes of exposure to EM waves respectively, and a positive control with no exposure to EM waves. Each treatments had 3 aureus on Flucloxacillin were the basis for the mutagenic potential of the cellular phone emission. Zones of inhibition were recorded after 24 hours. Analysis and interpretations of the data obtained revealed that the zones of inhibition decreaed as the duration of exposure increased. It was therefore concluded that EM cellular emissions decreases the suceptibility of aureus on Flucloxacillin.