This experimental study aimed to determine the antibacterial synergism of ethanollic talisay (terminalia catappa) and caballero (caesalpinia pulcherrima) leaf extract against staphylococcus aureus. There were 4 concentrations for their synergism. The positive control was flucloxacillin. The bacteria was provided by the Microbiology Department of West Visayas State University. It was standardized to 0.5 Mcfarland's standard. The agar well diffusion method was utilized to measure the antibacterial activity of the plants. The plates were incubated for 24 hours at 37 degrees celcius. Results showed that the combination of the ethanolic leaf extracts of Talisay and Caballero exhibited a higher antibacterial effect against S. aureus compared to that of the individual plants' extracts. The 75% talisay + 25% caballero showed the highest antibacterial activity among the concentrations but it was not as efefctive compared to the positive control.