The study was undertaken to determine the sustainability of the Magindanawon upland rice farming in 10 purposively selected barangays. These barangays are situated along the Rio Grande de Mindanao covering four municipalities: Carmen, Kabakan, Matalam and President Roxas, all of Cotabato, Philipines. Sustainability was measured using the following indicators: ecological friendliness , social justice, equity, cultural, acceptability, economic viability, technological soundness. The correlational research design and survey method in data gathering using personal interview technique was employed. A total of 108 farming households was selected from the ten barangays which served as the unit of analysis. Data were analyzed using descriptive statistics, Pearson product Moment Correlation and multiple regression. Result of the analysis showed the household respondent had low educational attainment. The mean was 6.7 equivalent to elementary level. The respondent farming experience had a mean of 21.84 years, their average farm size was 1.67 hectares. Majority (91.7%) were owner operator with the mean farm income of P13,037.96 pesos/ hectare of rice and that more than one- half of the respondent 63.9 percent of them are members of non-agricultural related organization. The farmer respondent claimed high accessibility in selling their rice products and that most (52.8%) of them availed of credit assistance from private traders. Radio was the respondents' most frequently cited source of agricultural information. In term of pest in the respondent farms useful insects were found to be still prevalent. Harmful insect like rice bug and stemborer might not too damaging considering that farmer respondent indicated "low infestation " in the Magindanawon upland farms. The soil in the respondent farms area was found fertile and erosion was not much at the time of the study. Land preparation and cultivation consisted of slashing, harrowing and furrowing were highly practiced by the respondent. Hill method of planting, grass cutting to control weeds, integrated pest management and traditional method to control pest and diseases were highly practiced by the household respondents,Convex bladed iron and sickel were used for harvesting. The farmer respondents use multi-purpose pavement solar dryers for drying their rice product. The overall sustainability of the Magindanawon upland rice farming was related moderate (77.93) Farm size, tenure status and farm income were found to have significant relationship with sustainability of Magindanawon upland rice farming. Also access to agricultural information was the farming support factor that was significantly associated with sustainability while crop pest incidence and soil fertility were the biophysical factors that significantly correlated with sustainability of Magindanawon upland farming. Moreover, cropping patterns, harvesting, drying and rituals were the farming found to be significantly associated with sustainability of upland farming. Farm income, crop pest incidence, educational attainment and access to agricultural information were the significant predictors of the Magindanawon upland rice farmers. Resolution of these problems was claimed to help attain peace and order these are the key in the holistic development in the area.