Comparative in vitro antibacterial activity of volatile oils of for species against hospital-acquired clinical isolates

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Author: Dela Rosa, Estrella P.

Accession Number: 1245T

Class No:

Author No: 1

Copyright Year: 1997

Abstract:

"Volatile oils extracted by steam-distillation from the rinds of "cajel"" (Citrus aurantium Linn), ""dalanghita"" (Citrus nobilis Lour), ""kalamansi"" (Citrus Microcarpa Bunge), and ""lukban "" (Citrus grandis Osbeck) were tested by the disk-diffusion method for antimicrobial activity against 156 bacterial clinical isolates and the reference strains Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Bacillus subtilis (ATCC 6633) Streptococcus sp., and Candida albicans (IPH 2179). Volatile oils of the four citrus species exhibited activity against the gram-positive reference bacteria only. the emost potent was ""darangita"" oil, followed by the oils of ""kalamansi"", ""cajel"", and ""lukban"". the most sensitive reference stain was S aureus, against which ""darangita"" oil had minimum inhibitory and minimum bactericidal concentration of 26.21 and 52.24mg/ml, respectively. For the 156 bacterial clinical isolates, the citrus oils were also effective only against the gram-positive isolates (55)of Staphylococcus. all citrus oil gave strong activities (Zone of inhibilitation)"


Keywords: volatile oils, hospital-acquired clinical isolates

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