This study aimed to determine the academic performance of pre-service science teachers of a state university who are exposed to mobile games. A Descriptive method of research was used, with the academic performance of pre-service science teachers as the dependent variable and (a) sex, (b) year level, (c) area of specialization and exposure to mobile games as the independent variables. The participants of the study were the 260 randomly - selected pre-service science teachers of West Visayas State University for the school year 2015-2016, second semester. Data were gathered utilizing the researcher-made test. The statistical tools used were the means, frequency count, standard deviation, ANOVA, and T-test. Based on the results of the study, the researchers found out that there was no significant relationship between exposure to mobile games and academic performance of pre-service science teachers of West Visayas State University. It was found out that mobile games do not affect the academic performance of pre – service science teachers, thus it is not a factor that influences their academic performance. It is recommended to make it as an action research since the researchers only used descriptive method of research. Since the results of this study showed that exposure to mobile games has no relationship to academic performance of pre – service science teachers, it is recommended to future researchers to conduct similar study with the new respondents from a different college or state university.