This descriptive correlation study entitled “Burnout Syndrome and Quality of Work Life: Its Implication to the Implementation of Health and Wellness Program” aimed to determine the level of burnout syndrome in terms of frequency and intensity and quality of work life of 79 faculty and staff and its implication to the implementation of health and wellness program of Calinog and other external campuses for the school year 2014-2015 when classified as to personal factors such as; age, sex and civil status and work-related factors. The results revealed that the burnout syndrome in terms of frequency and intensity of the respondents was “moderate”. The quality of life of the respondents was “very good”. The implementation of the Health and wellness program as perceived by the respondents was “implemented” to various degree except that the Hataw activity as physical fitness exercise, was “not implemented” as perceived by the respondents. The Mann Whitney test results for burnout syndrome revealed that burnout in terms of frequency differ significantly as to sex. Males had greater frequency of burnout than females. The Kruskal-Wallis test results for differences in the quality of work life showed that the respondents quality of work life differ significantly when classified as to SPMS performance. The Pairwise comparison on the quality of work life of the respondents revealed that respondents who belonged to the “Better” and “Best” categories had better quality than those who belonged to the “Good” category. Furthermore Mann-Whitney test results of significance on the quality of work life revealed that significant differences exist when the respondents were classified as to sex. Females had significantly higher quality of work life than males. No significant differences were noted in other categories of variables. Spearman's Correlation Results revealed significant positive correlation between burnout syndrome in terms of Frequency and Intensity. There exists significant negative correlation between burnout syndrome in terms of frequency and intensity and quality of work life. No correlation between quality of work life and health and wellness program.