The West Visayas State University research thrusts include health and environment. These thrusts coincide with Iloilo City’s all-out campaign for anti-smoking under the Iloilo City Ant-Smoking Task Force (ICAST) in their implementation of Regulation Ordinance No. 2006-150 or The Comprehensive Anti-Smoking Ordinance of Iloilo City. To help promote health, clean environment, and to partner with the city government in their initiative to completely ban smoking, this research project is divided into four studies: 1) cigarette smokers among elementary and high school students, 2) the level of awareness of students of cigarette smoking effects on the human body, 3) the effect of anti-smoking campaign materials and classroom demonstration on student knowledge and attitudes towards cigarette smoking, and 4) the degree of compliance of the city anti-smoking ordinance in school vicinities in Iloilo City. Study 1 made use of the Tobacco Questionnaire by the World Health Organization, Study 2 fielded a validated researcher-made questionnaire, Study 3 employed the pre-test post-test one group design, and Study 4 fielded an ocular survey, tallying, oral interview, and triangulation. Results showed that a majority of grade 6 and grade 10 students are non-cigarette smokers. For very few smokers, manufactured cigarettes were used because these were readily available and affordable for elementary and high school students. However, direct exposure to smoking at home from fathers, mothers, brothers, and others may affect their health and may further influence them to develop the habit of smoking. Grade 6 and grade 10 students have high level of awareness on smoking effects. This high level of awareness of the students may help in preventing them from cigarette smoking. There was a significant improvement in knowledge about smoking as students were exposed to anti-smoking campaign materials. The materials were effective in improving students’ knowledge on smoking and developing negative attitude towards smoking. The most effective campaign materials in developing negative attitudes towards smoking were video clips, followed by classroom demonstration, then posters, and brochures. Assessment of the extent of compliance of the Comprehensive Anti-Smoking Ordinance of Iloilo City around universities in Iloilo City by student observers, bystanders, and vendors showed about 60 % compliance, with about 40% violators. While researchers gave an on- the- spot assessment of 66.8% compliance, still a 38.2% effort is recommended to fully implement the Comprehensive Anti-Smoking Ordinance.