Programmed instruction in Chemistry was produced. The instrument used was patterned after that of Ticao (1986). It was face validated by jurors. The content and construct was validated by teachers. Factor analysis proved the validity of the evaluation of the programmed instruction in five learning areas, namely: (a) physical aspects, (b) objectives, (c) instructions, (d) learning activities, and (e) evaluative measures. The programmed instruction was evaluated "excellent" and "highly acceptable". It was tried out to one intact group of junior high school students. Results also showed a "fair" to "very satisfactory" pre and posttest scores in chemistry. Results also showed a significant difference in the pre-and posttest scores of the students. Programmed instruction improved junior students' performance in chemistry.